“Chloroquine is a potent inhibitor of SARS coronavirus infection and spread”

Virology Journal; Aug. 22, 2005

This was written 15 years ago, but this worked on SARS-CoV when nothing else seemed to, so if you ask me it’s kind of crazy to pretend that SARS-CoV, an 87% match with SARS-CoV-2, is not worthy of consideration (under medical supervision).

That’s the problem, doctors (and their expertise) have been overshadowed by tech people. I find this to be a big problem. Are we really supposed to believe Bill Gates and Mark Zuckerberg are the only people we should listen to? or the WHO, who is always putting its foot into its mouth and the point is, none of them actually solve the issue.

In the context of factbook they just censor and fact-check and make me look bad in front of my friends, and in every circumstance the fact-check was anything but a fact-check. We can only listen to Bill Gates, who is not a doctor. Sounds legit, right? No, of course it doesn’t. In the context of facebook, my posts about ‘the Rona’ were censored by a bunch of non-experts. It was so bad, that in January, I couldn’t snap a photo of the back of a Lysol can where it said that it “kill human coronaviruses” and “SARS coronavirus” (a fact). I can’t remember why they put a fact check on that one, because it was a tangent unrelated to my post (which happened quite often). So even when they were wrong or even unrelated, they left the fact checks up as if to say “do not listen to this man!”. Well.. I have my own site now.

Here is the abstract (and link to) the paper. Remember when they tried to scare us from hydroxychloroquine when they ran that story continuously about the guy that took a bunch of aquarium cleaner (which ended up being investigated as a murder and was quickly dropped by the media) to make a 60-70 year-old medicine sound as if it were poisonous? This is likely why. The solution already existed and is inexpensive and widely available.

Abstract

“Background

Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.

Results

We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.

Conclusion

Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.”

Accessible at: https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69